PASSAGE OF INTRAVENOUSLY INFUSED ATROPINE INTO PERFUSED CEREBRAL VENTRICLES AND SUBARACHNOID SPACE
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Passage of intravenously administered tubocurarine into the liquor space in man and dog.
1. In anaesthetized patients under controlled respiration, samples of lumbar cerebrospinal fluid were withdrawn 15 and 60 min after an intravenous injection of 30 mg tubocurarine. When tested on the frog rectus muscle preparation contracted by acetylcholine, they exerted curare-like activity which corresponded to between 0.05 and 0.33 mug/ml tubocurarine.2. In dogs anaesthetized with pentobarbi...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1966
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1966.tb01637.x